File:Reelin controls directed growth of radial fibers - journal.pone.0001454.g005 center cropped.jpg

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Reelin_controls_directed_growth_of_radial_fibers_-_journal.pone.0001454.g005_center_cropped.jpg ‎(498 × 295 pixels, file size: 143 KB, MIME type: image/jpeg)


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Summary

Description Reelin controls directed growth of radial fibers. (A) Schematic illustration of slice culture. After GFP plasmid electroporation, quail embryonic slices (E7) are co-cultured with Reelin and/or RFP-expressing COS7 cells (magenta). (B and C) Patterns of radial glial fiber extension in slices with control cells (B) and with Reelin-expressing cells (C). Straight projection of GFP-labeled radial fibers is evident with Reelin-expressing cells compared with control cells. (D) Quantification of radial fiber orientation. The parallel index (PI) of radial fibers was calculated by dividing the maximum distance between adjacent radial fibers by the minimum distance. Differences in PI between slices with control and Reelin-expressing cells were analyzed statistically (F-test). PI is reduced in Reelin-treated slices compared with that in control slices. Asterisks indicate statistically significance (p<0.01, F-test). Scale bar, 20 µm.
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Nomura T, Takahashi M, Hara Y, Osumi N. Patterns of neurogenesis and amplitude of Reelin expression are essential for making a mammalian-type cortex. PLoS ONE. 2008 Jan 16;3(1):e1454. PMID 18197264 doi: 10.1371/journal.pone.0001454 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2175532&rendertype=figure&id=pone-0001454-g005

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This is a retouched picture, which means that it has been digitally altered from its original version. Modifications: Cropped with only center remaining to present at Reelin page. The original can be viewed here: Journal.pone.0001454.g005.jpg: . Modifications made by CopperKettle.

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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.

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    • 2008-07-12T09:10:28Z CopperKettle 498x982 (206479 Bytes) {{Information |Description= Reelin controls directed growth of radial fibers. (A) Schematic illustration of slice culture. After GFP plasmid electroporation, quail embryonic slices (E7) are co-cultured with Reelin and/or RFP-

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current17:36, 12 July 2008Thumbnail for version as of 17:36, 12 July 2008498 × 295 (143 KB)CopperKettle{{Information |Description=Reelin controls directed growth of radial fibers. (A) Schematic illustration of slice culture. After GFP plasmid electroporation, quail embryonic slices (E7) are co-cultured with Reelin and/or RFP-expressing COS7 cells (magenta)

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