File:Canine-CNGA3-Gene-Mutations-Provide-Novel-Insights-into-Human-Achromatopsia-Associated-pone.0138943.s001.ogv

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Canine-CNGA3-Gene-Mutations-Provide-Novel-Insights-into-Human-Achromatopsia-Associated-pone.0138943.s001.ogv ‎(Ogg multiplexed audio/video file, Theora/Vorbis, length 27 s, 640 × 480 pixels, 1.02 Mbps overall, file size: 3.31 MB)


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Summary

Description
English: Clinical evidence of achromatopsia in R424W mutant based on behavioral vision testing under photopic and scotopic light conditions. Subjective vision testing shows complete loss of vision during daylight hours, but normal visual performance under dark, twilight, artificial, and low-level fluorescent light conditions. Movie illustrates visual behavior in the R424W-affected dog that is similar to what was observed in dogs homozygous for V644del mutations.
Date
Source S1 Fig from Tanaka N, Dutrow E, Miyadera K, Delemotte L, MacDermaid C, Reinstein S, Crumley W, Dixon C, Casal M, Klein M, Aguirre G, Tanaka J, Guziewicz K (2015). "Canine CNGA3 Gene Mutations Provide Novel Insights into Human Achromatopsia-Associated Channelopathies and Treatment". PLOS ONE. DOI:10.1371/journal.pone.0138943. PMID 26407004. PMC: 4583268.
Author Tanaka N, Dutrow E, Miyadera K, Delemotte L, MacDermaid C, Reinstein S, Crumley W, Dixon C, Casal M, Klein M, Aguirre G, Tanaka J, Guziewicz K
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inception

25 September 2015

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application/ogg

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data size

3,467,869 byte

duration

27.070666666666668 second

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480 pixel

width

640 pixel

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current01:57, 6 October 201527 s, 640 × 480 (3.31 MB)Open Access Media Importer BotAutomatically uploaded media file from Open Access source. Please report problems or suggestions here.

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